In a straight line the Avalon and V6 accord are pretty close, the avalon has more power but also weighs more. You can also get the V6 accord with a 6 speed which is NO contest against the avalon. The accord V6 automatic and avalon are both low 15 second high 14 second cars in the 1/4 mile, the Accord V6 6 speed is a low to flat 14 second car, it is significantly faster. In terms of handling there is no contest. The Avalon is a smooth refined midsized sedan aimed at the low end luxury market. The accord V6 is aimed at the midsized sport sedan/coupe market and as such it's suspension is set up more towards handling.If you want more luxury feeling, get the Avalon. If you want performance while still maintaining a bit of finesse go for the V6 accord 6 speed.